Hypoxia cures Parkinson's

Pretty cool stuff, I think. There was a time before modern medicine where societies used to send people with mental disorders to high altitude. The idea was that the air was cleaner up there and this would help them get better.

Now, we take a mouse that has Parkinson's and we put that mouse in an atmosphere that mimics life at 15,000 feet (11% oxygen). The symptoms of Parkinson's goes away. Then these geniuses develop a pill that mimics hypoxia by targeting hemoglobin. And THAT also takes a buzzsaw to Parkinson's symptoms in mice. It doubled the lifespan of mice in a Parkinson's disease model.

Yowza. We have to thank decades of research by investigators at the NIH and around the world.

https://www.pnas.org/doi/10.1073/pnas.2618654123